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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '34392bc09bee26791dbbf0dd21eafb770c0e59da2f161fdb487aabadb016ea73' 
  AND token = 'r6S1io+AfNDxLzwrsHthRWDN0uqRRJ7YRtqP+vLfNrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}