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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'afaf4e6ba2435f6a4ce3a215bc954c1b56d096cba385c7841d18f641194e4646' 
  AND token = '7SmAMh3n+NoNenaDWrUtp+tnYFiZXbaoXfDxVIeJhgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}