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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'b1a0198108c949a61bee15cbef011099a6918ae18a1aa177752512213d0cb8bf' 
  AND token = 'SbIK/cE0+7kbgp9QkKfRft+KsdzhfzBgDKpVD3a49Nw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}