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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4aeccdc21ab2c19e472279f671465fd3f07c79603aa8cf66c12c21e7d1621b52' 
  AND token = 'rXZDNupxLvSZtiw6qDMx28JNtrWYs+E3Qjg+CxjbFW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}