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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '40a62183247b4b9a00d0663cac7053f908ef3dcb17b212745e33dbe041c2e2a8' 
  AND token = 'C1U1Y1eBsB7NtWMDV3qzO3EyVSt+T5xsWoRZPce6VhY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}