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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'a37c3d35474b15abf9fe3e3c162fed4160aad87afec7e8a2815be02ecf233883' 
  AND token = '6YiNf1CLQRItldjJqvwC6lNcFqp6A8Fso6laXmRPDQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}