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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2023e9e7d9b071360c81000afb1e78624c578e996c47fe40de1201b3faf1fc40' 
  AND token = 'UfY2RhDABKITaapiOA19siCT/eud3mKu4fICgBfwDZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}