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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '49e251eb5b89c008d74836da1cad37e484660e6ca6cac17d1fd799c6835a7f66' 
  AND token = 'YIBUpT6tbJoR1yGLf7NOXWrxpyCqxN17JLFUkdma0+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}