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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '247f1b6d4594401a0dfaa674f24e9a68c094e43249a46ab94af0a0461b143208' 
  AND token = '5RV6qqPppwpGTYfo7V9L7sD73K45frc/0q52GnASdnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}