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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '0b011be8aa4bea3663773c53b16e2e617408694197a457cb7e74302731c2429e' 
  AND token = 'bKEmsaZO6ZtIlvg1fqSWHg8xTn+nEH2HtSA5hdRu+SA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}