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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '787001054295b454072ed5d2c21a1324fd8dee34938bd1a71064a9e73f2a1683' 
  AND token = 'waELWbqQSvxx2QXHOxK26Gq622cEqlU+R6sDS6Qh53A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}