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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'dcf8f3efcd5bda278d2e4af20ffc49d5603518096e74f8e93971cf8286547884' 
  AND token = 'O3MU8OW8H1EWjJcN1pWEROwpqdqXeNxTlFp6C3aCGeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}