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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'a7f10a8781535a83667a2554a51fd57bdf3031dba548af2e047cdd530a6a80dc' 
  AND token = '6OqAfiGw/qCq1NwYMkxUZ+a80qNEBzGWWsPyI+nFNl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}