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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '8706203f0c42eddec793de816512b0f7407da7fb3095aea7fb1f1afc25ddbe1d' 
  AND token = 'plpd0HKtY9M8YspXWA1WGEmQEqpvXeU4eh6edOPtONg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}