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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '8b48b332ae15663ab92b5781cc6af603d8d552edec7cd4d781a9d92a1a2b142e' 
  AND token = 'vDG3rE2aTxLkuwUjXAQRYoti1cetGPOUPHknUGKWu2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}