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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'b48f748a359e44bca4869ff49a7875efe06bbcc998db71c644fb1c7a298c0cd5' 
  AND token = 'WzvS0Uko3WFvavaA40Ma/ieT/EA46Eh+IpTwOH/ZkZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}