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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2b39ea4248565ac8342d11460efd78e4c43308ef0690f0119b39f0fb08c418f4' 
  AND token = '4YkmkaPRtkhN4HVHavnADXOdmQVM10VcDsmNaR49Dho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}