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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'd2345dc1f229125c3259ce62b76d3a532421a0118e6429b0e2cab5780b8a701c' 
  AND token = 'eOaRmkuxWc4t3GqGY5gMQHE2BzAYLlQRGTHK8+Y9tdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}