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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2d0e8ff6a31f592396370405e5879091ff51741a52a74b6ecf6b53514a2189a2' 
  AND token = '8BIc9tVxfT5jtaUL/a8SyAGreVTMXjvANTC5ldB26mA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}