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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '0f0f457a4499330f0fbe433c0018e603e271478a5bc1ff41178773988cfa0c40' 
  AND token = '622HXjPsV+0liXgG3tdEwUL424Qyy3PEDZOqcyLMcE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}