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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'b7280e25170b832b4f35517208f3b0e74dd4a74f18aa11a5fe121cec49d77f0c' 
  AND token = 'X0gsEfKM+Kd08fY2jUAkuraU4o3VFuLfeDZLja22TVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}