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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '441f2143217e7f44f65ae93f06af0e3c733ed517545b5a5b726e917b65a0287c' 
  AND token = 'mbufgFd+JhTX7noomlFyMx8rJ6kyEz+YrezkkntOFNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}