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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '497d67ed715eef23dc8827c1e853c1c900dd23654e671f1f5dd96aaefa0c4170' 
  AND token = 'J2liN38uxBHWGe0Qp2wgoQkRRKEN9uO0FBk93FMfpv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}