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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '16a7f23075fdd5d8648cd0e2f9712fd74c41d99bb6cc444e1208844bd710eada' 
  AND token = 'DMexEfO9KNteGlKnhyUR7eCaxYgCgKWuOAhFtoec9VU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}