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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '846316a9eb8eeec66223904fbb28bc9b23312fc891b7c7d930a3aad61a050491' 
  AND token = 'Wy7rbYpArjhpphEmfc9vUlebjd4lW5Rc37zhucyYIEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}