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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '25df3a9966cce68d64f82fb8149904b26a2263a9ea5a75e52fde493ad1bb7ac7' 
  AND token = 'nlK2zE4129xWr5yXlS31uT/8YDwTnPP0Mu/pv239blU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}