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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '9266f5487f14f050fda7000d4d4d840eafe9df1c3fa996a018df321570642f88' 
  AND token = 'mE/1FrZE/6mdgkRVlqPgAaZeamjgYrJj8ogRPYKKoe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}