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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '24ed1f8f8b8e25532b83eb4e10d2c5191e96d0d558ec419ad905deb3bcec1693' 
  AND token = 'pAN0IXR6CCnI04efTYb3Jcq4fTePMpgiYOXCtEw/fqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}