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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '680578bbfd0d646f21fb53f2b79acc8c7c99898a4f3699cc68afc660a4b2be24' 
  AND token = 'O2S18a483C7jhUxpNVR12dsZe4I8fPs11nUxPuvMCoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}