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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '647e18afdd0b0ed27cafd17134f3470dd17368f12a26166ebd31109935fb75ba' 
  AND token = 'L7N2RATG29i0tbyG8X6nGqu2LYdrNjFa2f3inOWHA9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}