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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'bd25ec0261123c79ceb46db2d8c8fb68df80aa2b0cdc2ca604427f5d5b053164' 
  AND token = 'VNGkihVQscS12NhGDyOycMPnq2n9wPNVQb+1CczByig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}