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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '740dc676200858d305ad4314e15dd89a0360979218789bf399a3fd007a68b9d9' 
  AND token = 'SD4ZwqkZEag5S7ld2CQKjJMEJAbnqeAzynpgd6zSeP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}