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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'af6c0bbcb6565bccfd6ac4f4fe14fe6ed4d703d9c9e2bb3acbb147b607d45f42' 
  AND token = 'laU+dMo+BOMH4mAxyZv1zAVzsMoAxNV7TOzH34yiU+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}