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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'a1eb001ed412e3204ee6abfea6d5efd3d6e1fb16256c948da6e9796261095699' 
  AND token = 'CUfwmJ4t2RPa47wr3D1f/C07x9rf6tDuA3HveD6v7Hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}