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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '6a80219f89d97f667a5be9cf97d4c82432d79ab3de719a0c32045b16c1b8d270' 
  AND token = 'NFfPQ563r/erXs8V/42X8/i3VdefHvxRjmHbgp4RA1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}