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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '3e36e810050dd1619da1eaa0c6be1696677e6d2d33c43beb6c6e7d677270a209' 
  AND token = 'kp4IMI2vhgNB8YXwqbreMD9ewM4KNDBM5Xw+lbChC24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}