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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '0edc98e6aa14a315391e9f1dbdfd4d13d3b867d9b2dd5b7a7e525613d88bfd53' 
  AND token = 'D2Uft4R4hCWivK8uTigM+dfWV45CJ26BAza4BtXyelg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}