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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '872e7e555e290aaeed76c864c22e8a12fe7cfe4ae407a50303e0516299c5092a' 
  AND token = 'uH7tYSD0p1DEcnM0YQm4IQy5s33q+h68fDDDBMzOhNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}