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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '5901a8a6b34c2250745f1f9da944c992c3e8356c1f52c92ef9e01eab26851242' 
  AND token = 'b90YAJCCpMJdpvOo5SR7wOZ2EixFis0cnCfRUPNjFy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}