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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'b6e3f58737034abe166be29c325057e93d1c556ac082aada72601ac335ed1c3e' 
  AND token = '03MtLDNqO3mv5IeoWB5quYd891SRPyIRk82UeRcitK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}