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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '380980e989cdc877e3929031caea5c9522f91e11ce9b585e6f178d9aa9bb0df2' 
  AND token = 'VzEaLS+fSaiGZXvD/hQ7AK1xLsnFv6fNcYIxssiA2Z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}