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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '58d23ab8c8abe73163205d583b8b4bbe25b839c65c03712d62f7df7848a41b6b' 
  AND token = 'PMO777mQkvCghi8HDb3eqlmx20HxwOTDPeJIhgSbO5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}