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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '9f5d49468e332f009989a785e00a54dd57c053a7dd1a6268993971d78d68383d' 
  AND token = 'THSFblUjBAHBuo2sU90v+ZdEdgXHewdVSVDpriVfvy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}