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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4245d2a5fa5f7034a5537f6df39ab2fe76c9be93caeafecf0621b7e425060b41' 
  AND token = 'WdoNXeUKouUuby22KFxg2b8Ra1wiAcSl8RKyzxHWM28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}