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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'b2054737356b6d15f0f3adaa32e37119f7f13925c04ea6c273d357fd7b5ff349' 
  AND token = 'Jw7RbUD79yij6cA/7xtnTb8lRhrYzFkBff4S9ByjZwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}