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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '7616bc004f15c90de2055d98a3f1cd23e9ef2166138c2069df7d6525dffdf66b' 
  AND token = 'zTD/Dde+giENeGN7PXtVuSNrAipRlLWiZ7Tj8JxaOOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}