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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '83f15a65b377ae9391b29c8e3870883f351e94ceb48c9dce828548c20cf204ea' 
  AND token = 'PHk0VQeF59oMPsR+YWY4iM8MRj+XfsZcoNe0RoFRhfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}