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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '25247c5544b1fb4f446b3b4abd4d24939aea21d24def6cde673327c97d7e5eae' 
  AND token = 'y/UeVYgGL+QX+NCXOio5Q8Bvftlugpb0V3M3tBRQpqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}