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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '50e8478c9f5184c84ef69aa406773da95f801dbfdca11f825d2a2ab2deaee9c0' 
  AND token = 'cs1ENz5AmNmUG7zlYsDbNmQuJQOwm1eNIRm9CUC/a2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}