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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '8afe86c9d66afd8d2ced47965275c9964e085d947d721f87c6daf4a1adc6b2ad' 
  AND token = 'am3XUSbh1gMUJwxtu85x1bQ9Rrp+fTAP4opSpQWlNE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}